Inhibitory effects and actions of pentacyclic triterpenes upon glycation

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Inhibitory effects and actions of pentacyclic triterpenes upon glycation

Pentacyclic triterpenic compounds including asiatic, betulinic, maslinic, oleanolic and ursolic acid occur naturally in many herbs and plant foods. It is well known that these triterpenoids possess anti-oxidative and anti-inflammatory activities. Furthermore, recent in vitro and in vivo researches indicated that these compounds could inhibit the production of advanced glycation end-products (AG...

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Anti-inflammatory actions of pentacyclic triterpenes.

Pentacyclic triterpenes (PTs) as aglycones of saponins have a wide distribution in plants, and many of them have been used as anti-inflammatory remedies in folk medicine. This survey critically reviews the effects of PTs on proinflammatory mediator signalling pathways and data from experimental animal models and clinical trials. Because the knowledge of their actions is far from being satisfact...

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Phenolic Compounds and Pentacyclic Triterpenes

Decoctions, macerations and fumigations of the stem bark and wood of Terminalia brownii 20 Fresen. are used in traditional medicine for fungal infections and as pesticides on field crops and in 21 traditional granaries in Sudan. In addition, T. brownii is commonly used for protecting wooden 22 houses and furniture. Therefore, using agar disc diffusion and macrodilution methods, eight extracts 2...

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Biosynthesis of p-Sitosterol and Pentacyclic Triterpenes of Salvia oficinaZk*

As Heftmann, Bennett, and Bonner have indicated (l), considerable information has accumulated concerning the biosynthesis of sterols in animals (2) and fungi (3), yet practically nothing is known about the biogenesis of typically higher plant sterols or the numerous pentacyclic triterpenes that are widely distributed throughout the plant kingdom. As yet, it cannot be assumed that the over-all b...

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Biologically active pentacyclic triterpenes and their current medicine signification

Pentacyclic triterpenes are produced by arrangement of squalene epoxide. These compounds are extremely common and are found in most plants. There are at least 4000 known triterpenes. Many triterpenes occur freely but others occur as glycosides (saponins) or in special combined forms. Pentacyclic triterpenes have a wide spectrum of biological activities and some of them may be useful in medicine...

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ژورنال

عنوان ژورنال: BioMedicine

سال: 2015

ISSN: 2211-8039

DOI: 10.7603/s40681-015-0013-x